Alan Shearer's eight-match reign as Newcastle manager began with a 2-0 loss to Chelsea on Saturday, illustrating the size of task the Magpies' former captain faces in trying to keep the club in the Premier League.
Second-half goals from Frank Lampard and Florent Malouda allowed title-chasing Chelsea to spoil the return of Newcastle's all-time leading goalscorer.
Newcastle is third from bottom, two points adrift of Sunderland which lost 2-0 at West Ham.
West Bromwich Albion and Middlesbrough, who occupy the bottom two places, also lost.
Blackburn moved four points clear of the relegation zone, stunning 10-man Tottenham with two late goals to come from behind and produce a 2-1 win.
In the chase for Champions League places, Arsenal strengthened its grip on fourth with Emmanuel Adebayor's double providing a 2-0 victory over Manchester City. The forward was playing in his first game for the Gunners after a two-month injury layoff.
In Saturday's late match, Liverpool was at Fulham looking to regain top spot from Manchester United until at least Sunday when the defending champions host Aston Villa.